منابع مشابه
Role of oxidative stress in rabies virus infection.
Recent studies in an experimental model of rabies indicated that there are major structural changes in the brain involving neuronal processes that are associated with severe clinical disease. Cultured adult mouse dorsal root ganglion (DRG) neurons are a good in vitro model for studying the mechanisms involved in rabies virus-induced degeneration of neurites (axons) because, unlike other neurona...
متن کاملHemagglutination by rabies virus.
Goose erythrocytes were agglutinated by five strains of rabies virus grown in monolayer cell cultures at pH 6.4 and at 0 to 4 C. Hemagglutination was not affected by the cell type in which the virus was grown. Prerequisites for occurrence of hemagglutination are absence of hemagglutination inhibitors (such as those contained in bovine serum) and a relatively high virus concentration (> 10(6) pl...
متن کاملRabies virus antinucleoprotein antibody protects against rabies virus challenge in vivo and inhibits rabies virus replication in vitro.
We previously reported that A/WySnJ mice vaccinated via a tail scratch with a recombinant raccoon poxvirus (RCN) expressing the rabies virus internal structural nucleoprotein (N) (RCN-N) were protected against a street rabies virus (D. L. Lodmell, J. W. Sumner, J.J. Esposito, W.J. Bellini, and L. C. Ewalt, J. Virol. 65:3400-3405, 1991). To improve our understanding of the mechanism(s) of this p...
متن کاملEPIDEMIOLOGICAL SURVEY OF DIFFERENT RABIES VIRUS STRAINS IN IRAN
Rabies is widespread in all provinces of Iran. This study presents an investigation by a Polymerase Chain Reaction (PCR) technique for the purpose of rabies diagnosis and also Restriction Fragment Length Polymorphism (RFLP) for determination of the type of the rabies virus. In addition, PCR proves to be a powerful tool for molecular epidemiology studies allowing analysis of the infecting strain...
متن کاملA recombinant rabies virus expressing vesicular stomatitis virus glycoprotein fails to protect against rabies virus infection.
To investigate the importance of the rabies virus (RV) glycoprotein (G) in protection against rabies, we constructed a recombinant RV (rRV) in which the RV G ecto- and transmembrane domains were replaced with the corresponding regions of vesicular stomatitis virus (VSV) glycoprotein (rRV-VSV-G). We were able to recover rRV-VSV-G and found that particle production was equal to rRV. However, the ...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2016
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro.2016.167